The hormone melatonin is one of the most powerful sources of antioxidants. It regulates our sleep and wakefulness and defends the body against excessive oxidative stress. Melatonin is vital for the immune system to help our body to repair and rejuvenate at the cellular level. This hormone slows down all processes in the body, helping it to recover and increases the level of serotonin in the brain. Melatonin deficiency can cause circadian rhythms disruption, sleep disorders and many serious and life-threatening mental and physiological diseases. 

Science is Clear About Characteristics And Benefits of Melatonin: 

  • promotes sleep 

  • its timely secretion helps to balance and harmonize the circadian rhythms 

  • suppresses appetite 

  • regulates blood pressure 

  • regulates blood sugar and insulin production 

  • it is the most effective antioxidant and a powerful free radical scavenger 

  • interacts with the immune system to fight cancer, infections, and inflammations 

  • inhibits early puberty 

  • plays a role in innate immunity 




Melatonin deficiency can cause circadian rhythms disruption, sleep disorders and many serious and life threatening mental and physiological diseases.

Natural Melatonin

Our bodies naturally produce endogenous melatonin. Endogenous means growing or originating from within an organism. Endogenous melatonin is at its highest level around midnight and subsides gradually to a very low level by the time we wake up in the morning. After 30 minutes exposure to daylight, or artificial bright light, it naturally subsides to its minimum daily level.

Natural melatonin, secreted by the pineal gland in the brain, triggers many of the night rhythms. Darkness stimulates its release into the brain and bloodstream while light inhibits it. Once released, it binds to hormonal receptors located in the brain’s suprachiasmatic nucleus, a cluster of nerves that regulates the body’s internal clock and circadian rhythms, and travels into cerebrospinal fluid and the bloodstream.

It was believed the brain only could produce melatonin in total darkness until research showed that it is only the blue wavelengths of the light spectrum which suppress the secretion of melatonin. When blocking the blue light, the brain behaves as if it is experiencing total darkness and triggers the melatonin secretion. Research demonstrates that melatonin modulates brain activity in a manner resembling actual sleep although subjects are fully awake.

Electric lights and electronic screens all emit blue light capable of signaling virtual daylight to the brain. Presence of blue light causes the brain to suppress secretion of melatonin, disrupting sleep and circadian rhythms associated with night. If the brain detects a change in lighting, it triggers the release of the stress hormone to quickly awaken the body. Therefore, it is important to sleep 6-8 hours a day and only in darkened environments. It is also important to have 10-11 hours of darkness for the brain i.e. lack of blue light 2-3 hours before sleep. Excessive blue light exposure and its devastating effects on our overall health is the subject of many scientific studies at the moment.



When blocking the blue light, the brain behaves as if it is experiencing total darkness and triggers the melatonin secretion.

Synthetic Melatonin

What ends up on pharmacy shelves is synthesized “exogenous” melatonin supplements, which means growing or originating from outside an organism. The amount of exogenous melatonin in the body has to do with dosage and the capacity of the body to absorb it. It can last way into the early hours of the next day keeping the user groggy. 

Melatonin supplement/drug is considered natural, but synthetically produced, the hormone is one of the murkiest supplements on the market, unsubstantiated by incomplete and developing research. Only in the U.S. is melatonin available over-the-counter as a dietary supplement, and long-term usage can alter natural hormone levels and even sabotage sleep.

Given to children, its potential side effects using synthetic melatonin is even more concerning. Since melatonin is a hormone, it can affect puberty, disrupt menstrual cycles and impede normal hormonal development.  Excess melatonin can induce hypothermia, as body temperatures reduce during melatonin release, and stimulate overproduction of the hormone prolactin, which can cause hormonal problems and even kidney and liver issues in men.



Given to children, its potential side effects using synthetic melatonin is even more concerning. 



Circadian Eyewear is a natural choice for increasing the level of endogenous/natural melatonin. Our ORPHEUS lens is designed, developed and engineered to provide a balanced light transmission while eliminating the blue light. Fine-tuned in world’s leading laboratories, our lens eliminates virtually all blue light.

Wearing the eyewear two hours before scheduled sleep time enables the body to produce its own melatonin hormone. By blocking the blue light, it sends a virtual darkness signal to the suprachiasmatic nucleus in the brain via dedicated photoreceptors in the retina. The master clock in turn starts the secretion of melatonin in merely 30 minutes. This synchronizes the circadian rhythms without having to compromise the lures of the night and the body will naturally get rid of it within half an hour after exposure to bright lights.  

Circadian Eyewear Collection 


Wearing the eyewear two hours before scheduled sleep time enables the body to produce its own melatonin hormone.


Research from PubMed 
Blue blocker glasses impede the capacity of bright light to suppress melatonin production 

Blocking low-wavelength light prevents nocturnal melatonin suppression with no adverse effect on performance during simulated shift work 

Dark therapy for bipolar disorder using amber lenses for blue light blockade 

Amber lenses to block blue light and improve sleep: a randomized trial 

Protecting the melatonin rhythm through circadian healthy light exposure 

Alterations of the circadian melatonin rhythm by the electromagnetic spectrum: a study in environmental toxicology 

Role of circadian rhythm and endogenous melatonin in pathogenesis of acute gastric bleeding erosions induced by stress 

Effects of blue light on the circadian system and eye physiology 

Melatonin and Peripheral Circuitries: Insights on Appetite and Metabolism in Danio Rerio 

Antioxidative effect of melatonin on DNA and erythrocytes against free-radical-induced oxidation 

Influence of Dietary Melatonin on Photoreceptor Survival in the Rat Retina: An Ocular Toxicity Study

Research Sources